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1.
Biomédica (Bogotá) ; 43(3): 360-373, sept. 2023. tab, graf
Article in Spanish | LILACS | ID: biblio-1533947

ABSTRACT

Introducción. Las tasas de éxito del tratamiento de la tuberculosis continúan siendo subóptimas. Objetivo. Identificar los factores asociados al tratamiento no exitoso para tuberculosis en pacientes con antecedentes de tratamiento para la tuberculosis. Materiales y métodos. Se realizó un estudio observacional retrospectivo, analítico, de cohorte de pacientes que reingresaron a un programa de micobacterias en Cali, Colombia. Se incluyeron mayores de 15 años con tuberculosis pulmonar entre el 2015 y el 2019 con antecedentes de tratamiento para la tuberculosis. Se excluyeron los pacientes con tuberculosis resistente. Resultados. Ingresaron 605 pacientes con antecedentes de tratamiento, 60 % por tratamiento inconcluso y 40 % por recaída. En comparación con los pacientes que reingresaron por recaída (ORa= 2,34; IC=1,62-3,38), las variables que explicaron de manera independiente el no tener éxito con el tratamiento para la tuberculosis al egreso fueron: estar en situación de calle (ORa = 2,45; IC = 1,54-3,89), ser farmacodependiente (ORa = 1,95; IC=1,24-3,05), tener coinfección tuberculosis/VIH (ORa = 1,69; IC =1,00- 2,86) o diabetes (ORa =1,89; IC=1,29-2,77), y el incumplimiento de un tratamiento previo por pérdida de seguimiento, abandono u otras causas. Las variables programáticas que favorecieron el éxito del tratamiento fueron la asesoría de la prueba voluntaria de VIH (p < 0,001) y la realización de la prueba de VIH (p < 0,001). Conclusión. Estar en situación de calle, ser farmacodependiente, tener coinfección de tuberculosis y VIH, o diabetes, así como el incumplimiento del tratamiento previo por pérdida del seguimiento, abandono o fracaso del mismo, dificultaron el éxito del tratamiento antituberculoso. En la primera atención al reingreso de los pacientes con tuberculosis se deben identificar y abordar estas características.


Introduction. The success rates in the treatment of tuberculosis are suboptimal. Objective. To identify associated factors with the lack of success of antituberculosis treatment in patients with a tuberculosis treatment history. Materials and methods. We performed a retrospective, analytical, observational, and cohort study of patients reentering the Mycobacterium program in Cali, Colombia. We included patients over 15 years old with pulmonary tuberculosis between 2015 and 2019 and a history of tuberculosis treatment. Patients with drug-resistant tuberculosis were excluded. Results. A total of 605 patients with a treatment history were included, 60% due to unfinished treatment and 40% due to relapse. Compared to patients reentering due to relapse (ORa=2.34, CI=1.62-3.38), the independent variables associated with treatment failure at discharge were homelessness (ORa=2.45, CI=1.54-3.89), substance dependence (ORa=1.95, CI=1.24-3.05), tuberculosis/HIV coinfection (ORa=1.69, CI=1.00-2.86), diabetes (ORa=1.89, CI=1.29-2.77), and unfinished previous tuberculosis treatment due to follow-up loss, abandonment, or other causes. Programmatic variables favoring treatment success were voluntary HIV testing counseling (p<0.001) and HIV testing (p<0.001). Conclusion. Homelessness, substance dependence, tuberculosis/HIV coinfection, diabetes, and incomplete previous treatment due to loss to follow-up, abandonment, or treatment failure hindered the success of antituberculosis. These characteristics should be identified and addressed during the initial care of patients reentering treatment for tuberculosis.


Subject(s)
Tuberculosis , Tuberculosis, Pulmonary , Epidemiologic Factors , Communicable Disease Control , Treatment Adherence and Compliance , Health Services Accessibility
2.
Espaç. saúde (Online) ; 24: 1-12, 01 mar. 2023. ilus
Article in Portuguese | LILACS | ID: biblio-1428495

ABSTRACT

Malformações congênitas (MC) são alterações estruturais/funcionais que ocorrem no feto trazendo impacto socioeconômico e emocional. Estudo retrospectivo, documental, de abordagem quantitativa, com o objetivo de identificar a relação dos fatores de risco e perfil epidemiológico materno com a ocorrência de MC. Baseou-se na análise de 37 prontuários de gestantes em município da região metropolitana de Curitiba-PR, entre 2019 e 2021. Os achados revelaram um perfil: gestantes entre 18 e 36 anos, multíparas, obesas, com comorbidades, sem avaliação pré-concepcional. Os sistemas orgânicos mais acometidos foram o cardiovascular, o nervoso ou múltiplos sistemas. Identificou-se risco aumentado de malformações fetais em mulheres maiores de 25 anos, obesas, que utilizaram álcool ou tabaco. Embora uma causa única das MC nesse período e local não tenha sido identificada, estabeleceu-se associação entre fatores epidemiológicos maternos e características das malformações fetais, evidenciando necessidade de educação em saúde pré-concepcional


Congenital malformations (CM) are structural/functional alterations that occur in the fetus, leading to a socio-economic and emotional impact. This is a retrospective, documentary study with a quantitative approach aiming at identifying the relationship of risk factors and maternal epidemiological profile with the occurrence of CM. It was based on the analysis of 37 medical charts of pregnant women in a municipality in the metropolitan region of Curitiba-PR, between 2019 and 2021. The data revealed a profile: pregnant, multiparous, obese women between 18 and 36 years old, with comorbidities, with no preconception evaluation. The most affected organic systems were the cardiovascular and the nervous systems or multiple systems. An increased risk of fetal malformations was observed in obese women over 25 years old, who used alcohol or tobacco. Although a single cause of CM in that period and place has not been identified, an association was established between maternal epidemiological factors and characteristics of fetal malformations, highlighting the need for preconception health education.


Las malformaciones congénitas (MC) son alteraciones funcionales que ocurren en el feto, llevando consigo un impacto socioeconómico y emocional. Estudio retrospectivo, documental, con abordaje cuantitativo, con el objetivo de identificar la relación entre los factores de riesgo y el perfil epidemiológico materno con la ocurrencia de MC. Se basó en el análisis de 37 prontuarios de embarazadas del municipio de la región metropolitana de Curitiba-PR, entre 2019 y 2021. Los hallazgos revelaron un perfil: embarazadas entre 18 y 36 años, multíparas, obesas, con comorbilidades, sin evaluación preconcepcional. Los sistemas orgánicos más afectados fueron los sistemas cardiovascular, nervioso o múltiple. Se identificó un mayor riesgo de malformaciones fetales en mujeres mayores de 25 años, obesas, consumidoras de alcohol o tabaco. Aunque no se ha identificado una causa única de MC en ese período y lugar, se estableció una asociación entre los factores epidemiológicos maternos y las características de las malformaciones fetales, destacando la necesidad de la educación sanitaria previa a la concepción


Subject(s)
Prenatal Care , Congenital Abnormalities , Epidemiologic Factors
3.
Psicol. ciênc. prof ; 43: e250675, 2023. tab
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1448938

ABSTRACT

Em março de 2020 a situação causada pela covid-19 foi elevada à categoria de pandemia, impactando de inúmeras formas a vida em sociedade. O objetivo deste estudo foi compreender os impactos da pandemia na atuação e saúde mental do psicólogo hospitalar, profissional que atua nos espaços de saúde e tem experienciado mais de perto o sofrimento dos doentes e dos profissionais de saúde frente à covid-19. Trata-se de um estudo exploratório-descritivo com 131 psicólogos que atuam em hospitais. Os profissionais foram convidados a participar através de redes sociais e redes de contatos das pesquisadoras, utilizando-se a técnica Bola de Neve. Foram utilizados dois questionários, disponibilizados na plataforma Google Forms, um abordando os impactos da pandemia sentidos pelos profissionais e outro referente ao sofrimento psíquico. Os dados foram analisados a partir de estatísticas descritivas e inferenciais. Foram observados impactos na atuação de quase a totalidade dos participantes, constatada a necessidade de preparação dos profissionais para o novo cenário, a percepção de pouco apoio institucional e quase metade da população estudada referiu-se a sintomas de sofrimento psíquico considerável desde o início da pandemia. É fundamental dar atenção a sinais e sintomas de sofrimento psíquico, procurando evitar o adoecimento de uma categoria profissional que se encontra na linha de frente do combate aos danos psicológicos da pandemia e cuja própria saúde mental é pouco abordada na literatura.(AU)


In March 2020, the COVID-19 pandemic breakout hugely impacted life in society. This study analyzes how the pandemic impacted hospital psychologists' mental health and performance, professional who more closely experienced the suffering of patients and health professionals in this period. An exploratory and descriptive study was conducted with 131 hospital psychologists. Professionals were invited to participate through the researchers' social and contact networks using the Snowball technique. Data were collected by two questionnaires available on the Google Forms platform, one addressing the impacts felt by professionals and the other regarding psychic suffering, and analyzed by descriptive and inferential statistics. Results showed that almost all participants had their performance affected by the need to prepare for the new scenario, the perceived little institutional support. Almost half of the study sample reported considerable psychological distress symptoms since the beginning of the pandemic. Paying attention to signs and symptoms of psychic suffering is fundamental to avoid compromising a professional category that is on the front line of combating the psychological damage caused by the pandemic and whose own mental health is little addressed by the literature.(AU)


En marzo de 2020, la situación provocada por el COVID-19 se caracterizó como pandemia e impactó el mundo de diversas maneras. El objetivo de este estudio fue comprender los impactos de la pandemia en la salud mental y la actuación del psicólogo en los hospitales, uno de los profesionales que trabaja en espacios sanitarios y que ha experimentado más de cerca el sufrimiento de pacientes y profesionales sanitarios frente al COVID-19. Este es un estudio exploratorio descriptivo, realizado con 131 psicólogos que trabajan en hospitales. Los profesionales recibieron la invitación a participar a través de las redes sociales y redes de contactos de las investigadoras, mediante la técnica snowball. Se utilizaron dos cuestionarios disponibles en la plataforma Google Forms: uno sobre los impactos de la pandemia en los profesionales y el otro sobre el sufrimiento psíquico. Los datos se analizaron a partir de estadísticas descriptivas e inferenciales. Se observaron impactos en el trabajo de casi todos los participantes, la necesidad de preparación de los profesionales para este nuevo escenario, la percepción de poco apoyo institucional, y casi la mitad de la población estudiada reportaron sentir síntomas de considerable angustia psicológica desde el inicio de la pandemia. Es esencial prestar atención a los signos y síntomas del sufrimiento psíquico, buscando evitar la enfermedad de una categoría profesional que está a la vanguardia de la lucha contra el daño psicológico de la pandemia y cuya propia salud mental se aborda poco en la literatura.(AU)


Subject(s)
Humans , Female , Adult , Middle Aged , Young Adult , Psychology , Mental Health , Coronavirus Infections , Pandemics , Anxiety , Orientation , Physicians , Protective Clothing , Respiration , Respiratory Tract Infections , Safety , Attention , Set, Psychology , Social Adjustment , Social Isolation , Stress, Physiological , Stress, Psychological , Awareness , Software , Immunoglobulin M , Adaptation, Psychological , Pharmaceutical Preparations , Irritable Mood , Family , Carrier State , Epidemiologic Factors , Public Health Practice , Quarantine , Sanitation , Hygiene , Public Health , Epidemiology , Risk , Disease Outbreaks , Data Collection , Survival Rate , Mortality , Transportation of Patients , Triage , Contact Tracing , Occupational Health , Immunization , Universal Precautions , Infection Control , Immunization Programs , Infectious Disease Transmission, Professional-to-Patient , Infectious Disease Transmission, Patient-to-Professional , Coronavirus , Comprehensive Health Care , Disease Transmission, Infectious , Remote Consultation , Containment of Biohazards , Pulmonary Ventilation , Emergency Plans , Disaster Vulnerability , Declaration of Emergency , Disaster Planning , Death , Trust , Air Pollution , Ethanol , Economics , Emergencies , Emergency Services, Psychiatric , Empathy , Ethics, Professional , Professional Training , Surveillance of the Workers Health , Family Relations , Family Therapy , Resilience, Psychological , Infectious Disease Incubation Period , Fear , Epidemics , Social Networking , Binge Drinking , Epidemiological Monitoring , Personal Protective Equipment , Emotional Adjustment , Emergency Medical Dispatch , Survivorship , Family Separation , Posttraumatic Growth, Psychological , Embarrassment , Sadness , Teleworking , Physical Distancing , COVID-19 Nucleic Acid Testing , SARS-CoV-2 , Sociodemographic Factors , Suicide Prevention , Post-Acute COVID-19 Syndrome , Health Services Research , Immune System , Sleep Initiation and Maintenance Disorders , Anger , Loneliness , Masks , Mass Media , Negativism , Nurses, Male , Nursing Assessment
4.
Rev. Bras. Saúde Mater. Infant. (Online) ; 22(4): 803-812, Oct.-Dec. 2022. tab, graf
Article in English | LILACS | ID: biblio-1422687

ABSTRACT

Abstract Objectives: to assess factors associated with early weaning and the pattern of spatial distribution of breastfeeding in the ascription territory of a Basic Health Unit (BHU). Methods: analytic cross-sectional study performed with 47 mothers of children under 2 years of age in a BHU from Vitória de Santo Antão, Pernambuco. The association of independent variables and early weaning was verified using bivariate and multivariate analysis. For spatial analysis of cases of breastfeeding, we applied Kernel density estimation, proximity analysis buffers of the addresses of participants to the Health Unit and flow map. Results: the prevalence of early weaning was 61.7% (CI95% = 47.8-75.6). Factors associated with early weaning were: distance of residence to the BHU higher than 500 meters, not being primiparous, non-participation in educational groups for pregnant women during prenatal period and use of nursing bottles. Being beneficiary of welfare program Bolsa Família and residing in a home with piped water constituted a protective factor for this outcome. Two clusters of early weaning cases were found in locations further away from the BHUs. Conclusions: there was high prevalence of early weaning and association of this outcome with the home-health unit displacement, being primiparous, non-participation of pregnant women in educational activities during prenatal period and use of nursing bottles.


Resumo Objetivos: avaliar os fatores associados ao desmame precoce e o padrão de distribuição espacial do aleitamento materno no território de adscrição de uma Unidade Básica de Saúde (UBS). Métodos: estudo analítico transversal realizado com 47 mães de crianças menores de dois anos em uma UBS, de Vitória de Santo Antão, Pernambuco. A associação entre as variáveis independentes e o desmame precoce foi verificada por meio de análise bivariada e multivariada. Para análise espacial dos casos de aleitamento materno, empregou-se a técnica de densidade de Kernel, buffers de proximidade dos endereços das participantes à Unidade de Saúde e mapa de fluxo. Resultados: a prevalência de desmame precoce foi de 61,7% (IC95%= 47,8-75,6). Os fatores associados ao desmame precoce foram: distância da residência para a UBS maior de 500 metros, não ser primípara, não participação no grupo educativo de gestante durante o pré-natal e o uso de mamadeira. Receber bolsa família e residir em domicílio com água encanada constituíram fator de proteção a esse desfecho. Encontrou-se dois aglomerados de casos de desmame precoce em locais mais afastados da UBS. Conclusões: houve alta prevalência de desmame precoce e associação deste desfecho com o deslocamento domicílio-unidade de saúde, primiparidade, não participação da gestante em atividades educativas durante o pré-natal e utilização de mamadeira.


Subject(s)
Humans , Female , Infant, Newborn , Infant , Weaning , Breast Feeding , Health Centers , Epidemiologic Factors , Spatial Analysis , Sociodemographic Factors , Brazil
5.
rev.cuid. (Bucaramanga. 2010) ; 14(1): 1-12, 20221221.
Article in Spanish | LILACS, BDENF, COLNAL | ID: biblio-1428744

ABSTRACT

Introducción: La Diabetes Mellitus tipo 2 es una enfermedad que representa un reto para la salud pública por su tendencia al crecimiento e impacto sobre todo en países en desarrollo. Objetivo: determinar los factores asociados a la no realización del cribado de diabetes mellitus tipo 2 según la encuesta demográfica y de salud familiar del año 2020 (ENDES-2020). Materiales y métodos: Estudio analítico transversal secundario de la ENDES-2020. Resultados: Las variables que mostraron asociación estadísticamente significativa para cribado de DM2 fueron: sexo masculino (PR=1,06, IC95% 1,02­1,10; p<0,001), edad entre 30 a 59 años (0,92; IC95% 0,89­0,95; p<0,001) y 60 años a más (PR=0,72; IC95% 0,65­0,79; p<0,001), educación primaria (PR=0,94, IC 95% 0,92 - 0,99; p<0,020), secundaria (PR=0,93; IC 95% 0,88­0,97; p=0,008) y superior (PR=0,86, IC 95% 0,85­0,94; p<0,001), ser pobre (PR=0,96, IC95% 0,92­0,99; p=0,016), medio (PR=0,93; IC95% 0,88 ­ 0,96; p=0,001), rico (PR=0,89; IC95% 0,84 ­ 0,94; p<0,001), muy rico (PR=0,81; IC95% 0,75­0,86; p<0,001), e hipertensión (PR=0,91; IC 95% 0,867­0,969; p=0,002). Discusión: El sexo masculino fue el único factor asociado a la no realización del cribado de diabetes mellitus tipo 2, mientras que, pertenecer a un grupo de edad mayor, tener hipertensión arterial, mayor nivel educativo y socioeconómico aumentó la posibilidad de realizarlo. Conclusión: Es imprescindible reforzar las estrategias de cribado en el primer nivel de atención, mediante la implementación de medidas de prevención.


Introduction: Type 2 Diabetes Mellitus (T2DM) is a disease that poses a challenge to public health due to its growth trend and impact, especially in developing countries. This study aimed to determine the factors associated with not being screened for T2DM according to the 2020 Demographic and Family Health Survey (ENDES-2020). Materials and Methods: Secondary, cross-sectional, analytical study using the ENDES-2020 data. Results: The variables that showed a statistically significant association for T2DM screening were the following: male sex (PR=1.06, 95% CI: 1.02­1.10; p<0.001), ages between 30 and 59 years (0.92, 95% CI: 0.89­0.95; p<0.001) and 60 years and older (PR=0.72, 95% CI: 0.65­0.79; p<0.001), primary education (PR=0.94, 95% CI: 0.92­0.99; p<0.020), secondary education (PR=0.93, 95% CI: 0.88­0.97; p=0.008) higher education (PR=0.86, 95% CI: 0.85­0.94; p<0.001), poor (PR=0.96, 95% CI: 0.92­0.99; p=0.016), middle income (PR=0.93, 95% CI: 0.88­0.96; p=0.001), rich (PR=0.89, 95% CI: 0.84­0.94; p<0.001), very rich (PR=0.81, 95% CI: 0.75­0.86; p<0.001), and hypertension (PR=0.91, 95% CI: 0.867­0.969; p=0.002). Discussion: Being male was the only factor associated with not being screened for T2DM, whereas belonging to an older age group, having arterial hypertension, and having higher education and socioeconomic levels increased the possibility of being screened. Conclusion: It is essential to strengthening screening strategies at the primary level of care by implementing preventive measures.


Introdução: A diabetes melito tipo 2 é uma doença que representa um desafio à saúde pública devido a sua crescente tendência e impacto, especialmente em países em desenvolvimento. O objetivo deste estudo foi determinar os fatores associados à não realização de triagem para diabetes mellitus tipo 2 de acordo com a Pesquisa Demográfica e de Saúde da Família 2020 (DHS-2020). Materiais e métodos: Estudo analítico transversal secundário do ENDES-2020. Resultados: As variáveis que mostraram associação estatisticamente significativa para a triagem DM2 foram: sexo masculino (PR=1,06, 95%CI 1,02-1,10, p<0,001), idade 30-59 anos (0,92, 95%CI 0,89-0,95, p<0,001) e 60 anos ou mais (PR=0,72, 95%CI 0,65-0,79, p<0,001), educação primária (PR=0,94, 95%CI 0,92-0,99, p<0,020), educação secundária (PR=0,93, 95%CI 0,88-0,97, p=0,008), e educação secundária superior (PR=0,93, 95%CI 0,88-0,97, p=0,008); p=0,008) e superior (PR=0,86, 95% CI 0,85-0,94; p<0,001), pobre (PR=0,96, 95% CI 0,92-0,99; p=0,016), médio (PR=0,93, 95% CI 0,88 - 0,96; p=0,001), rica (PR=0,89; 95%CI 0,84 - 0,94; p<0,001), muito rica (PR=0,81; 95%CI 0,75-0,86; p<0,001), e hipertensão (PR=0,91; 95%CI 0,867-0,969; p=0,002). Discussão: O sexo masculino foi o único fator associado com a não realização de triagem para diabetes mellitus tipo 2, enquanto pertencia a uma faixa etária mais velha, ter hipertensão, educação superior e status socioeconômico aumentou a probabilidade de triagem. Conclusão: É essencial reforçar as estratégias de triagem no nível da atenção primária através da implementação de medidas preventivas.


Subject(s)
Peru , Epidemiologic Factors , Mass Screening , Diabetes Mellitus
6.
Rev. peru. med. exp. salud publica ; 39(4): [463-468], oct. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1424347

ABSTRACT

La malaria en Colombia tiene un comportamiento heterogéneo y variable, entre las regiones. Para establecer su comportamiento epidemiológico en la región del Caribe colombiano entre 1960 y 2019 se realizó un estudio observacional, descriptivo y retrospectivo a partir de registros del Ministerio de Salud y otras fuentes secundarias. Se definieron variables epidemiológicas y se elaboraron medidas de frecuencia y tendencia central. Se registraron 155 096 casos. Las décadas con mayor número de casos fueron 1990-1999 (20,5%) y 1980-1989 (18,9%). El promedio de casos por década fue de 25 849,3. Los índices parasitarios más elevados se registraron en 1970 (3,3 por 1000 habitantes) y 1981 (3,9 por 1000 habitantes). La especie Plasmodium vivax fue la más frecuente y la mayoría de la carga por grupos de edad se registró en menores de 29 años, entre 2010-2019. La malaria presentó un patrón endemo-epidémico de baja y muy baja intensidad de transmisión, con una tendencia al descenso.


Malaria has a heterogeneous and variable behavior among Colombian regions. In order to establish its epidemiological behavior in the Colombian Caribbean region between 1960 and 2019, we carried out an observational, descriptive and retrospective study based on records from the Ministry of Health and other secondary sources. We defined epidemiological variables and used measures of frequency and central tendency. A total of 155,096 cases were registered. The decades with the highest number of cases were 1990-1999 (20.5%) and 1980-1989 (18.9%). The average number of cases per decade was 25,849.3. The highest parasite rates were recorded in 1970 (3.3 per 1000 population) and 1981 (3.9 per 1000 population). Plasmodium vivax was the most frequent species and most of the burden by age group was found in people under 29 years of age, between 2010-2019. Malaria showed an endemic-epidemic pattern of low and very low transmission intensity, with a decreasing trend.


Subject(s)
Plasmodium vivax , Public Health , Vector Borne Diseases , Malaria , Plasmodium falciparum , Epidemiologic Factors , Disease Outbreaks , Caribbean Region
7.
Medicentro (Villa Clara) ; 26(3): 614-636, jul.-set. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1405660

ABSTRACT

RESUMEN Introducción: El trasplante renal es la mejor opción disponible para el tratamiento de la insuficiencia renal crónica terminal. La determinación de marcadores humorales permite detectar y seguir la evolución del paciente trasplantado renal y la disfunción del injerto, así como sus diversas complicaciones. Objetivos: Relacionar el funcionamiento del trasplante renal realizado a pacientes con un grupo de marcadores humorales. Métodos: Se realizó una investigación descriptiva y de corte transversal en 85 pacientes trasplantados renales, previo consentimiento informado, los cuales constituían la totalidad de los pacientes del Servicio de trasplante renal, en el Hospital Universitario Clínico-Quirúrgico «Arnaldo Milián Castro¼, Santa Clara, Villa Clara, desde enero de 2015 a diciembre de 2017. Resultados: Predominaron pacientes del sexo masculino, de 40-59 años de edad. La principal enfermedad asociada fue la hipertensión arterial. Del total de trasplantados estaban con funcionabilidad 62 pacientes (72,94 %) y en ellos, fue significativo el aumento de los valores de hematocrito y albúmina, así como el valor medio de la creatinina sérica, ligeramente superior a los valores de referencia. Conclusiones: El rango de edad más frecuente fue de 40-59 años. Prevaleció el sexo masculino asociado con la hipertensión arterial. Predominó la funcionabilidad de los trasplantes realizados precozmente, con menor tiempo en diálisis. En los marcadores humorales la creatinina presentó una asociación significativa. Por otra parte, el hematocrito nunca se normalizó en los no funcionales. El conteo de Addis fue el examen que más modificación precoz sufrió ante cualquier alteración en la función renal.


ABSTRACT Introduction: renal transplantation is the best available option for the treatment of terminal chronic renal failure. The determination of humoral markers makes it possible to detect and follow the evolution of kidney transplant patients and graft dysfunction, as well as its various complications. Objectives: to relate the performance of kidney transplants performed in patients with a group of humoral markers. Methods: a descriptive and cross-sectional research was carried out in 85 kidney transplant patients, with prior informed consent, which constituted all the patients of the Kidney Transplant service from "Arnaldo Milián Castro" Clinical and Surgical University Hospital, Santa Clara, Villa Clara, between January 2015 and December 2017. Results: male patients aged 40-59 years old predominated. The main associated disease was arterial hypertension. A number of 62 patients from the total number of transplant recipients (72.94%) were functional and the increase in hematocrit and albumin values ​​was significant in them, as well as the mean value of serum creatinine was slightly higher than the reference values. Conclusions: the most frequent age range was 40-59 years. The male gender associated with arterial hypertension prevailed. The functionality of transplants performed early, with less time on dialysis, prevailed. Creatinine had a significant association in the humoral markers. On the other hand, the hematocrit never normalized in non-functional patients. The Addis count was the test that underwent the earliest changes in the event of any alteration in renal function.


Subject(s)
Biomarkers , Epidemiologic Factors , Kidney Transplantation , Renal Insufficiency, Chronic
8.
Rev. Ciênc. Méd. Biol. (Impr.) ; 21(1): 73-78, maio 05,2022. fig, tab
Article in English | LILACS | ID: biblio-1370699

ABSTRACT

Introduction: envenomation and deaths by bee stings have increased in all regions of Brazil. However, there are few epidemiological studies on them, especially in the states of northeastern Brazil. Objective: to determine the epidemiological characteristics of bee stings in the state of Bahia, Northeastern Brazil, from 2010 to 2019. Methodology: this is a descriptive and analytical epidemiological study conducted through a retrospective survey of secondary data provided by the database of the Notifiable Diseases Information System of the Ministry of Health. Results: between 2010 and 2019, a total of 7,979 cases were analyzed. Incidents were distributed in 356 municipalities, with the highest frequency in the regions of Agreste and Sertão da Bahia. Cases occurred in all months of the investigated years, with a greater occurrence in urban areas, affecting mainly adult men. The anatomical region of the body most affected by the sting was the head and most cases received medical care within 3 hours after the incident. Local manifestations were more frequent than systemic ones. The injuries were predominantly classified as mild and progressed to cure. Conclusions: the high number of cases and their extensive spatial distribution reveal that bee stings may be considered an emerging and neglected public health problem in the state of Bahia.


Introdução: os acidentes e os óbitos causados por picada de abelha têm aumentado em todas as regiões do Brasil. Contudo, existem poucos estudos epidemiológicos sobre acidentes com abelha, principalmente nos estados do Nordeste do Brasil. Objetivo:determinar as características epidemiológicas do acidente por picada de abelha no estado da Bahia, Nordeste do Brasil, de 2010 a 2019. Metodologia: trata-se de um estudo epidemiológico descritivo e analítico realizado por meio de uma pesquisa retrospectiva de dados secundários disponibilizados pelo banco de dados do Sistema de Informação de Agravos de Notificação do Ministério da Saúde. Resultados: entre 2010 e 2019, um total de 7.979 casos foi analisado. Os acidentes foram distribuídos em 356 municípios, com a maior frequência nas regiões do Agreste e do Sertão da Bahia. Os casos ocorreram em todos os meses dos anos investigados, com maior ocorrência em áreas urbanas, afetando principalmente homens adultos. A região anatômica do corpo mais atingida pela picada foi a cabeça e a maioria dos casos recebeu assistência médica até 3 horas após o incidente. As manifestações locais foram mais frequentes do que as sistêmicas. Os agravos foram predominantemente classificados como leve e progrediram para a cura. Conclusões: o elevado número de casos e a sua extensa distribuição espacial revelam que o acidente causado por picada de abelha pode ser considerado um emergente negligenciado problema de saúde pública no estado da Bahia.


Subject(s)
Humans , Animals , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Bees , Insect Bites and Stings/epidemiology , Brazil/epidemiology , Epidemiologic Factors , Retrospective Studies
10.
Rev. Eugenio Espejo ; 16(1): 71-80, 20220111.
Article in Spanish | LILACS | ID: biblio-1353012

ABSTRACT

La tuberculosis continúa siendo un problema de salud pública. Al respecto, se realizó un estudio no experimental de corte transversal, con el objetivo de caracterizar clínica y epidemiológica-mente el estado de la TB resistente a medicamentos de primera línea en la ciudad de Durán, desde enero 2015 hasta diciembre 2019. Los datos incluidos en los documentos de la matriz del programa de tuberculosis resistente. De 1111 casos nuevos de tuberculosis reportados en el cantón Durán durante el período estudiado, 45 de estos presentaron resistencia a medicamentos de primera línea. El 88,89% tuvo resistencia a rifampicina, el 33,33% de los pacientes se dispen-sarizaron en 2019. Los valores de chi cuadrado de Pearson no mostraron asociación estadística-mente significativa entre las variables investigadas (p>0,05). Entre los involucrados predominó el grupo de edades de 20 a 39 años, el sexo masculino, la tuberculosis pulmonar, infectados con VIH/sida, resistencia clasificada como primaria, los que abandonaron el seguimiento al trata-miento y la no manifestación de reacciones adversas a los medicamentos. No se observó mortali-dad entre los casos nuevos, predominando entre aquellos con recaída, el género masculino y los que tuvieron tuberculosis extrapulmonar.


Tuberculosis is a disease that continues to be a public health problem. In this regard, a non-expe-rimental cross-sectional study was carried out to characterize clinically and epidemiologically the status of TB resistant to first-line drugs in the city of Durán, from January 2015 to December 2019. The data included in the resistant tuberculosis program matrix documents. 1111 new cases of tuberculosis were reported in the Duran canton during the study period, 45 of these ones presented resistance to first-line drugs. 88.89% had rifampicin resistance, 33.33% of the patients were dispensed in 2019. Pearson's chi-square values did not show a statistically significant asso-ciation between the investigated variables (p> 0.05). Among the study population, it was predo-minated the age group between 20 and 39, male sex, pulmonary tuberculosis, infected with HIV / AIDS, resistance classified as primary, those who abandoned the follow-up to treatment and the non-manifestation of adverse drug reactions. No mortality was observed among new cases, predominantly among those ones with relapse, the male gender and those ones who had extra-pulmonary tuberculosis


Subject(s)
Humans , Male , Female , Adult , Patients , Tuberculosis , Drug Resistance , Therapeutics , Epidemiologic Factors , HIV
11.
Ghana med. j ; 56(4): 239-245, 2022. tables
Article in English | AIM | ID: biblio-1401980

ABSTRACT

Objective: The study assessed willingness to accept the COVID-19 vaccine among out-patient department (OPD) attendants in the Bono Region in Ghana. Design: This was an analytical cross-sectional study Setting: The study was conducted at the Wenchi Methodist Hospital (WMH) OPD, Bono Region, Ghana. The region had not yet been earmarked for vaccination at the time of the study. Participants: Three hundred and twenty-five (325) participants aged ≥18 years, accessing care at the OPD of WMH and willing to give informed consent, were interviewed.Main outcome measures: The proportion of participants willing to accept the COVID-19 vaccine and its determinants. Results: Of 325 participants interviewed, 32 (9.8%) had been vaccinated already. 82.6% (242/293) indicated COVID19 vaccine acceptance among the unvaccinated. The major reason for vaccine acceptance was "it could protect against COVID-19" (96.7%, 234/242). "Fear of vaccine side effects and "perception of not being susceptible to COVID-19" were among the reasons for vaccine refusal. Perceived susceptibility to COVID-19 (AOR 4.09, 95% CI 1.79, 9.34), knowledge of COVID-19 and COVID-19 vaccine (AOR 3.62, 95% CI 1.14, 11.46) and willingness to pay for the vaccine (AOR 5.20, 95% CI 2.49, 10.43) were associated with vaccine acceptance. Conclusions: Adequate knowledge of COVID-19 and the vaccine may drive vaccine acceptance in the study area and possibly other areas in Ghana. Campaign messages aimed at increasing COVID-19 vaccine coverage must emphasise its safety, likely side effects and management in order to help rid the population of misconceptions


Subject(s)
Humans , Epidemiologic Factors , COVID-19 , Behavior , Bacterial Vaccines , Ghana
12.
Ibom Medical Journal15 ; 15(3): 236-244, 2022. tables
Article in English | AIM | ID: biblio-1398762

ABSTRACT

Background:Knowledge on etiology, risk factors, mode of transmission, signs and symptoms of COVID-19 is an essential element in pandemic control. Assessing the level of knowledge and determining sources from which information were derived is a fundamental element of situation analysis imperative in COVID-19 control.Materials and method: The study is a cross sectional study. All eligible visitors who presented at the general out-patient department for Medicare were enlisted into the study until required sample size was achieved. Pre-tested interviewer administered questionnaire was used to elicit information from respondents. Statistical analysis was done with multinomial logistic regression analysis using SPSS version 23.1 with statistical significance set at 0.05. Ethical approval and permission for the study from relevant authorities were granted.Conclusion:Knowledge of COVID 19 was poor. Higher educational qualification enhances better knowledge. Females, public servants, married persons, respondents who attended tertiary institution and those aged 31-40 years had better knowledge score.Results:Over all composite score for good knowledge was 1037(35.4%) with predominant statistically significant difference in knowledge. There was better knowledge score for females, public servants, married persons, respondents aged 31-40 years and those who had tertiary education


Subject(s)
Humans , Epidemiologic Factors , Patient Medication Knowledge , COVID-19 , Sociology , Demography
13.
Rev. Méd. Inst. Mex. Seguro Soc ; 60(1): 40-43, 2022. tab
Article in Spanish | LILACS | ID: biblio-1359823

ABSTRACT

Introducción: en diciembre de 2019, el coronavirus 2 causante del síndrome respiratorio agudo severo (SARS-CoV-2) provocó un brote en Wuhan, China, de la enfermedad respiratoria denominada COVID-19. A finales de febrero de 2020 se detectó en México el primer caso de COVID-19. Con esta enfermedad, las enfermedades crónicas degenerativas son determinantes para que la comorbilidad continúe en aumento. Objetivo: conocer las características epidemiológicas y la comorbilidad en trabajadores enfermos de COVID-19 del Órgano de Operación Administrativa Desconcentrada Estatal Veracruz Norte, del Instituto Mexicano del Seguro Social (IMSS). Material y métodos: estudio descriptivo y transversal que incluyó a 228 pacientes de COVID-19, trabajadores del IMSS. Se analizaron variables como edad, género, así como unidad médica, categoría contractual, comorbilidades, etcétera, las cuales se tomaron de abril a junio de 2020 de la base del Sistema de Notificación en Línea para la Vigilancia Epidemiológica (SINOLAVE). Se empleó estadística descriptiva y chi cuadrada de Pearson, con una p < 0.05. Resultados: se analizaron 228 pacientes. El personal de enfermería fue el de mayor prevalencia, con 101 pacientes (44.3%). Las comorbilidades más frecuentes fueron la obesidad en primer plano, con 27 pacientes (11.8%), y la diabetes mellitus por sí sola con 15 (6.6%), y en conjunto, con hipertensión arterial, obesidad y ser fumador crónico se presentaron en 22 pacientes (9.6 %). Conclusiones: predominó el personal de enfermería; las comorbilidades prevalentes fueron la obesidad, la diabetes mellitus y la hipertensión arterial


Background: In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused an outbreak of the respiratory disease called COVID-19, in Wuhan, China. At the end of February 2020, it was detected in Mexico the first case of COVID-19. With this disease, chronic degenerative diseases are decisive for comorbidity to continue increasing. Objective: To know the epidemiological characteristics and comorbidity in workers sick with COVID-19 from the Veracruz Norte Regional Deconcentrated Administrative Operation Body, from the Mexican Institute for Social Security (Instituto Mexicano del Seguro Social, IMSS). Material and methods: Descriptive, cross-sectional study, which included 228 COVID-19 patients, who were IMSS workers. Variables such as age, gender, as well as medical unit, contractual category, comorbidities, etc., were analyzed and were taken from April to June 2020 from the Online Notification System for Epidemiological Surveillance (SINOLAVE) database. It was used descriptive statistics, and Pearson's chi-squared, with a p < 0.05. Results: 228 patients were analyzed. The nursing staff was the one with the highest prevalence with 101 patients (44.3%). Comorbidities such as obesity in the foreground, with 27 patients (11.8%), and diabetes mellitus alone with 15 patients (6.6%), and as a group, along with arterial hypertension, obesity and being a chronic smoker in 22 patients (9.6%) were the most frequent. Conclusions: The nursing staff predominated; the prevalent comorbidities were obesity, diabetes mellitus and arterial hypertension


Subject(s)
Male , Female , Adult , Middle Aged , Epidemiologic Factors , Health Personnel , Epidemiological Monitoring , SARS-CoV-2 , COVID-19 , Cross-Sectional Studies , Mexico
14.
Ann. afr. méd. (En ligne) ; 15(2): e4543-e4549, 2022. figures, tables
Article in English | AIM | ID: biblio-1366652

ABSTRACT

Context and objective. The steady increase in the number of chronic hemodialysis patients in sub-Saharan Africa (SSA) calls for improved management of those patients. The present study aimed to determine the frequency of hepatitis C virus (HCV) infection, the prevalent genotypes, and the risk factors associated with HCV in hemodialysis patients in Kinshasa (DR Congo). Methods. A cross-sectional study was conducted from February to June 2018 in all hemodialysis centers in Kinshasa. Blood samples were collected from 127 chronic hemodialysis patients and tested for the presence of antibodies against HCV. The HCV genotype was identified by real-time polymerase chain reaction (RT- PCR). Results. Twenty-two (17.3 %) patients were positive for anti-HCV antibodies, ranging from 0 % to 52.9 % in different centers. Genotype 4 was detected in 18/22 (81.8 %), followed by genotype 2 in 2/22 (9.1%), and both genotypes 2 and 4 in one patient (4.5%). One patient had an undetermined genotype (4.5 %). Having received at least 4 transfusions [7,21 (1,09- 10,61); p=0.040)], not being under EPO treatment [5,81(1,47-12,96); p=0.012)], being on hemodialysis for at least 14 months [3,63(1,60-5,05); p=0.035)]and being dialyzed in an overloaded center [2,06(0,83-5,86); p=0.073)] were associated with a greater risk of HCV infection. Conclusion. This high HCV prevalence (17.3 %) represents a substantial health burden in HD patients from Kinshasa, DR Congo. It is largely driven by the number of blood transfusions, the duration time in hemodialysis. Observations from the present study underscore the need of reducing the number of blood transfusions in people on dialysis through the administration of erythropoietin, given the unaffordable cost of HCV therapy for most individuals in DR Congo.


Contexte et Objectifs. Le nombre des patients hémodialisés en Afrique subsaharienne en constante augmentation ; justifiant de ce fait une meilleure prise en charge de ces patients. La présente étude détermine la prévalence de l'infection par le virus de l'hépatite C en en determinant les génotypes ainsi que les facteurs y associés dans ce groupe de patients. Méthodes. 127 patients hémodialisés chroniques ont subis des tests sérologiques à la recherche des anticorps anti-VHC dans plusieurs centres de Kinshasa de février à juin 2018. Le génotype viral a été déterminé par la RT-PCR. Résultats. La fréquence des anticorps anti-VHC a varié de 0 à 52,9 % dans ce groupe. Les génotypes le plus fréquents ont été le 4 (18/22) et le 2 (2/22) ; étant sumultanément rétrouvé chez un patient, et indéterminé chez un autre sujet. Avoir reçu au moins 4 transfusions [7,21 (1,09-10,61; p=0.040)], ne pas être sous EPO [5,81(1,47-12,96); p=0.012)], être en hémodialyse depuis au moins 14 mois [3,63(1,60- 5,05); p=0.035)] et être dialysé dans un centre surchargé [2,06 (0,83-5,86); p=0.073)] étaient associés à un risque plus élevé d'infection par le VHC. Conclusion. Ses principaux déterminants sont : le nombre des transfusions sanguines et la durée d'HD ; d'où la nécessité de réduire les transfusions sanguines chez les sujets dialysés par l'administration d'EPO, étant donné le coût prohibitif du traitement contre le VHC dans notre contexte


Subject(s)
Humans , Male , Female , Epidemiologic Factors , Hepacivirus , Genotype , Prevalence , Renal Dialysis
15.
Rev. peru. med. exp. salud publica ; 38(4): 608-614, oct.-dic. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1365941

ABSTRACT

Resumen Con el objetivo de evaluar las tendencias en el uso de fármacos en pacientes con la COVID-19 de un hospital del Perú durante la primera ola de la pandemia se realizó un estudio retrospectivo entre abril y septiembre del 2020. Se revisaron las historias clínicas de pacientes hospitalizados por neumonía por COVID-19 en el Hospital Nacional Dos de Mayo (Lima, Perú). De un total de 3103 pacientes, se incluyeron 381 historias clínica (77,4% varones y mediana de edad de 44 años). Se observó un incremento del uso de cuatro fármacos prehospitalarios (azitromicina, ivermectina, corticoides y ceftriaxona), y una disminución del uso de seis fármacos intrahospitalarios (ceftriaxona, azitromicina, hidroxicloroquina, ivermectina, pulso de corticoides y anticoagulación profiláctica); además, el uso de anticoagulación intrahospitalaria aumentó. Estos hallazgos sugieren que el manejo de la COVID-19 varió durante la primera ola de la pandemia, aumentando el uso de fármacos prehospitalarios y disminuyendo el uso de fármacos intrahospitalarios.


Abstract This study aimed to evaluate the pharmacological trends in patients with COVID-19 from a hospital in Peru during the first wave of the pandemic. Retrospective study conducted between April and September 2020. The medical records of patients hospitalized for COVID-19 pneumonia at the Dos de Mayo National Hospital (Lima, Peru) were reviewed. Of a total of 3103 patients, 381 medical records were included (77.4% male, median age: 44 years). The use of four prehospital drugs increased (azithromycin, ivermectin, corticosteroids, and ceftriaxone), while the in-hospital use of six drugs (ceftriaxone, azithromycin, hydroxychloroquine, ivermectin, corticosteroid pulse, and prophylactic anticoagulation) decreased and in-hospital anticoagulation use decreased. These findings suggest that the management of COVID-19 has varied during the first wave of the pandemic, typically increasing prehospital drug use and decreasing inpatient use.


Subject(s)
Humans , Male , Female , Peru , Pharmaceutical Preparations , Pandemics , COVID-19 , Pneumonia , Therapeutics , Dexamethasone , Epidemiologic Factors , Drug Utilization , Hospitalization , Anti-Bacterial Agents
16.
Salud bienestar colect ; 5(3): 105-128, dic. 2021. tab
Article in Spanish | LILACS | ID: biblio-1398553

ABSTRACT

El presente trabajo persigue los siguientes objetivos: a) Problematizar el concepto de territorio en la pandemia de COVID-19 a partir de la perspectiva de la determinación social. b) Describir socio-históricamente el territorio de atención de la salud en México. c) Establecer líneas de análisis de las expresiones del territorio de atención de la salud en México de acuerdo a los niveles estructurales macro, d) meso y e) micro. Los efectos de la infección biológica de un virus tienen una determinación social que a su vez reconfiguran un territorio covid que resalta los efectos tardíos de las políticas estructurales neoliberales encrudeciendo las desigualdades e inequidades socio históricas. El macro territorio Covid es complejo en sus determinaciones, estructurado a partir de la trama de actores de la implementación de las políticas donde sería preciso indagar la relación entre política sanitaria y territorio refiriéndonos a la singularidad de lo "sectorial" y a sus diferencias con otras lógicas como la "territorial", a fin de conformar un territorio-salud considerando los nudos críticos de desigualdades estructurales.


This paper has the following objectives: a) Problematize the concept of territory in the COVID-19 pandemic from the perspective of social determination. b) Describe socio-historically the territory of health care in Mexico. c) Establish lines of analysis of the expressions of the territory of health care in Mexico according to the macro, d) meso and e) micro structural levels. The effects of the biological infection of a virus have a social determination that in turn reconfigures a COVID territory that highlights the late effects of neoliberal structural policies, starving socio-historical inequalities and inequities.


Subject(s)
Humans , Pandemics , Social Determinants of Health/statistics & numerical data , COVID-19/epidemiology , Social Environment , Social Identification , Epidemiologic Factors , Health Status Indicators , Cultural Characteristics , Health Planning/organization & administration , Mexico
17.
Rev. enferm. Inst. Mex. Seguro Soc ; 29(3): 136-134, 04-oct-2021. tab
Article in Spanish | LILACS, BDENF | ID: biblio-1357685

ABSTRACT

Introducción: en la actualidad, el cáncer gástrico sigue ocupando un lugar importante entre las causas de muerte a nivel mundial. Objetivo: determinar las características sociodemográficas, ambientales y clínicas de los pacientes con cáncer gástrico en el municipio de San Gil, Colombia. Metodología: estudio descriptivo transversal. La muestra estuvo conformada por 13 casos de personas con diagnóstico clínico e histopatológico de cáncer gástrico del municipio de San Gil, Santander, residentes del área rural y urbana. El análisis estadístico fue realizado con el programa Statistical Product and Service Solutions, versión 24.0 Resultados: el género con mayor afectación fue el masculino con un 62%. La mediana de edad de los participantes fue de 51 años con una edad mínima de 36 años y una edad máxima de 87 años. En el 61.5% el nivel de escolaridad fue la educación primaria. En cuanto a los factores ambientales, se encontró que el 69.2% consumieron alimentos salados y condimentados. Conclusiones: se encontró que una gran proporción de los participantes fueron del género masculino y residentes del casco urbano. Entre las ocupaciones, las más frecuentes fueron amas de casa y conductores de transporte pesado. Los síntomas que presentaron los participantes en el momento del diagnóstico fueron: pérdida de peso, hematemesis, dolor epigástrico y sensación de plenitud abdominal


Introduction: At present, gastric cancer continues to occupy an important place among the causes of death worldwide. Objective: To determine the sociodemographic, environmental, and clinical characteristics of patients with gastric cancer in the municipality of San Gil, Colombia. Methods: Descriptive cross-sectional study. The sample consisted of 13 cases of people with clinical and histopathological diagnosis of gastric cancer from the municipality of San Gil, Santander, who were residents of rural and urban areas. Statistical analysis was carried out with the program Statistical Product and Service Solutions (SPSS), version 24.0. Results: Men were the most affected, with 61.5%. The median age of the participants was 51 years with a minimum age of 36 years and a maximum of 87 years. In 61.5% the level of education was primary education. Regarding environmental factors, it was found that 69.2% consumed salty and spicy foods. Conclusions: It was found that a large proportion of the participants were male, urban residents. Concerning occupations, the most frequent were housewives and heavy truck drivers. Symptoms that participants presented at the time of diagnosis were weight loss, hematemesis, epigastric pain and fullness in upper abdomen.


Subject(s)
Humans , Male , Female , Stomach Neoplasms , Epidemiologic Factors , Cross-Sectional Studies , Public Health , Cause of Death , Colombia
18.
Rev. cuba. med. mil ; 50(3): e1370, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1357301

ABSTRACT

Introducción: La cirrosis hepática representa en Perú el 9,1 por ciento de las causas de mortalidad. Existe poca evidencia sobre la influencia de variables epidemiológicas y clínicas en la mortalidad de pacientes con cirrosis hepática en Latinoamérica, en especial en países en vías de desarrollo, como Perú. Objetivo: Identificar los factores asociados a la mortalidad en pacientes cirróticos. Métodos: Estudio trasversal en pacientes cirróticos atendidos en el Hospital Cayetano Heredia, de Piura, Perú, en el año 2017. La variable dependiente fue la mortalidad hospitalaria y las variables independientes fueron las características epidemiológicas, clínicas y de laboratorio. Se utilizó la prueba exacta de Fisher y la prueba de t para estimar los factores asociados a la mortalidad. Resultados: De 52 pacientes, la frecuencia de mortalidad debido a cirrosis fue de 35,4 por ciento. Tener ascitis moderada (p = 0,004), grado de encefalopatía (p = 0,001), leucocitosis (p = 0,004), enfermedad descompensada según índice de Child Pugh (p = 0,023), índice de Meld entre 30-39 puntos (p < 0,001) y niveles de creatinina (p = 0,009) resultaron asociados a una mayor frecuencia de mortalidad. Conclusión: La presencia de ascitis moderada, grado de encefalopatía, leucocitosis, enfermedad descompensada según índice de Child Pugh, índice de Meld entre 30-39 y los niveles de creatinina, están asociados a la mortalidad en pacientes cirróticos(AU)


Introduction: Liver cirrhosis represents 9,1 percent of causes of mortality in Peru. There is little evidence on the influence of epidemiological and clinical variables on the mortality of patients with liver cirrhosis in Latin America, especially in developing countries such as Peru. Objective: To identify the factors associated with mortality in cirrhotic patients. Methods: Cross-sectional study in cirrhotic patients treated at the Cayetano Heredia Hospital in Piura, Peru, year 2017. The dependent variable was hospital mortality and the independent variables were epidemiological, clinical and laboratory characteristics. Fisher's exact test and the T test were used to estimate the factors associated with mortality. Results: Of 52 patients, the frequency of mortality due to cirrhosis was 35,4 percent. Have moderate ascites (p = 0,004), degree of encephalopathy (p = 0,001), leukocytosis (p = 0,004), decompensated disease according to the Child Pugh index (p = 0,023), Meld index between 30-39 points (p < 0,001) and creatinine levels (p = 0,009) were associated with a higher frequency of mortality. Conclusion: The presence of moderate ascites, degree of encephalopathy, leukocytosis, decompensated disease according to the Child Pugh index, Meld index between 30-39, creatinine levels are associated with mortality in cirrhotic patients(AU)


Subject(s)
Humans , Ascites/complications , Hospital Mortality , Liver Cirrhosis/mortality , Peru , Brain Diseases/mortality , Epidemiologic Factors , Cross-Sectional Studies
19.
Rev. habanera cienc. méd ; 20(4): e4112, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1289624

ABSTRACT

Introducción: Los pacientes fallecidos por COVID-19 al inicio de la pandemia evidencian características clínico-epidemiológicas particulares y su identificación, lo mismo que los aspectos asociados a su diagnóstico son fundamentales para la implementación de estrategias en salud pública que permitan la protección sanitaria de los grupos más vulnerables. Objetivo: Determinar las características clínico epidemiológicas de los pacientes fallecidos por COVID-19 y su asociación con el diagnóstico tardío en las primeras etapas de la pandemia en el departamento de Bolívar-Colombia. Materiales y Métodos: Estudio descriptivo de corte transversal con una muestra de 51 pacientes fallecidos por COVID-19; se calculó la frecuencia relativa de los factores de riesgo clínico epidemiológicos de estos pacientes y se realizó un análisis bivariado para evidenciar la asociación con la posibilidad de ser diagnosticado después de la muerte, usando la razón de disparidad (OR) con su intervalo de confianza Resultados: El 47,2 por ciento de los diagnósticos se hicieron después de la muerte; el promedio entre el inicio de los síntomas y la muerte fue aproximadamente 13 días, en los que se evidencia como comorbilidades importantes las enfermedades cardíacas (58,5 por ciento) y la hipertensión (35,8 por ciento). La asociación con el diagnóstico después de la muerte se relaciona con los casos notificados en abril y mayo (p=0,03), ser mayor de 80 años (p=0,03) y tener malnutrición (p=0,04). Conclusión: En el contexto del departamento de Bolívar se observan fallas en el diagnóstico oportuno de algunos grupos poblacionales vulnerables y a los pacientes con enfermedades cardíacas se debe prestar atención para evitar la alta mortalidad(AU)


Introduction: Patients who died from COVID-19 at the beginning of the pandemic show particular clinical-epidemiological characteristics and their identification as well as the aspects associated with the diagnosis are fundamental for the implementation of public health strategies that allow the sanitary protection of the most vulnerable groups. Objective: To determine the clinical-epidemiological characteristics of patients who died from COVID-19 and its association with late diagnosis in the early stages of the pandemic in the department of Bolívar-Colombia. Material and Methods: Descriptive cross-sectional study with a sample of 51 patients who died from COVID-19; the relative frequency of the clinical-epidemiological risk factors of these patients was calculated and a bivariate analysis was performed to show the association with the possibility of being diagnosed after death, using the disparity ratio (OR) with its confidence interval. Results: The 47,2 percent of the diagnoses were made after death; the average between the onset of symptoms and death was approximately 13 days, in which heart disease (58,5 percent) and hypertension (35,8 percent) were evidenced as important comorbidities. The association with diagnosis after death is related to the cases reported in April and May (p = 0.03), being older than 80 years (p = 0.03) and having malnutrition (p = 0.04). Conclusion: In the context of the department of Bolívar, failures are observed in the timely diagnosis of some vulnerable population groups, thus special attention should be paid to patients with heart disease to avoid high mortality(AU)


Subject(s)
Humans , Male , Female , Risk Groups , Vulnerable Populations/ethnology , Delayed Diagnosis/prevention & control , COVID-19/epidemiology , Heart Diseases/complications , Epidemiologic Factors , Epidemiology, Descriptive , Cross-Sectional Studies , Colombia , COVID-19/mortality
20.
Rev. Bras. Saúde Mater. Infant. (Online) ; 21(3): 925-934, July-Sept. 2021. tab
Article in English | LILACS | ID: biblio-1346994

ABSTRACT

Abstract Objectives: to describe the prevalence of sufficient leisure-time physical activity (LPA) in the trimesters of pregnancy and to test its association with sociodemographic and contextual characteristics. Methods: cross-sectional study that in 2019 analyzed data from 3580 pregnant women residing in Santa Catarina, Brazil. LPA was categorized as "active" (150 minutes or more of LPA/week) and "inactive" (less than 150 minutes). Results: the prevalence for the recommended level of LPA was 15.3% (CI95%= 14.1-16.4) before pregnancy, gradually declining to 7.8% (CI95%= 7.3-8.7), 7.3% (CI95%= 6.58.2), and 5.8% (CI95%= 5.1-6.7) in the following trimesters of pregnancy. Higher level of education was associated with the four outcomes, increasing the chance of being active by 79% in the third trimester of pregnancy. In the second trimester, living in a neighborhood that stimulates physical activity increased the chance of being active by 39%. In the third trimester, having received guidance from a health professional was associated with an increase of 60% in the chance of practicing LPA. Conclusion: the prevalence of recommended LPA is low among pregnant women and living in a neighborhood favorable to outdoor practices, greater education level and receiving guidance from health professionals increased the chance of pregnant women to be active.


Resumo Objetivos: descrever a prevalência de atividade física no lazer (AFL) suficiente nos trimestres da gravidez e testar sua associação com características sociodemográficas e contextuais. Métodos: estudo transversal que analisou em 2019 dados de 3.580 gestantes residentes em Santa Catarina, Brasil. AFL foi categorizada como "ativa" (150 minutos ou mais de LPA / semana) e "inativa" (menos de 150 minutos por semana). Resultados: a prevalência para o nível recomendado de AFL foi de 15,3% (IC95%= 14,116,4) antes da gravidez, diminuindo gradualmente para 7,8% (IC95%= 7,3-8,7), 7,3% (IC95%= 6,5-8,2), e 5,8% (IC95%= 5,1-6,7) nos trimestres seguintes da gravidez. Maior escolaridade foi associada aos quatro desfechos, aumentando a chance de ser ativa em 79% no terceiro trimestre da gravidez. No segundo trimestre, morar em um bairro que estimula a atividade física aumentou em 39% a chance de ser ativa. Já no terceiro trimestre, ter recebido orientação de profissional de saúde esteve associado a um aumento de 60% na chance de praticar AFL. Conclusão: a prevalência de AFL recomendada é baixa entre gestantes e morar em bairro favorável a atividades ao ar livre, maior escolaridade e receber orientação de profissionais de saúde aumentam a chance de gestantes serem ativas.


Subject(s)
Humans , Female , Pregnancy , Pregnancy Trimesters/physiology , Exercise/physiology , Prevalence , Pregnant Women , Leisure Activities , Prenatal Care , Socioeconomic Factors , Brazil/epidemiology , Epidemiologic Factors , Cross-Sectional Studies
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